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✔️ 標題 : A Mother's Story
✔️ 片長 :110 Minutes
✔️ 类型: 剧情
✔️ 語言 :粵語 (中文字幕)
✔️ 視頻解析度: 720p-1080p HD
✔️ 視頻格式 : mp4
✔️ 上映日期: 2011-11-06
✔️ 演員 :Pokwang, Xyriel Manabat, Nonie Buencamino, Rayver Cruz, Daria Ramirez, K Brosas, Ana Capri, Beth Tamayo, Jaime Fabregas, Alexis Navarro / 更多...
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OMIM Entry 480000 SEXDETERMINING REGION Y SRY ~ Goodfellow and LovellBadge 1993 provided a major review of SRY and sex determination in mammals From the study of normal males and females persons with abnormal numbers of sex chromosomes and persons carrying variant Y chromosomes a factor or factors that determines the differentiation of the indifferent gonads into testes is known to
Production of Sry knockout mouse using TALEN via oocyte ~ Construction of TALEN and the production of Sry KO mouse In order to generate Sry KO mouse we adopted the TALENmediated method instead of the conventional homologous recombinationbased ES cell modification strategy since Sry locates within 28 kb of a unique sequence at the center of a large inverted repeat structure 23
Evolution of the MaleDetermining Gene SRY Within the Cat ~ IN placental mammals SRY sexdetermining region on the Y chromosome termed Sry in the mouse is the maledetermining gene G ubbay et al 1990 S inclair et al 1990 and functions in early development to trigger a cascade of gene expression that result in testis formation C apel 1998 S wain and L ovellB adge 1999
The SRY gene ScienceDirect ~ The cloning of this gene marks the end of the beginning of our understanding of sex determination This review covers the structure of the SRY gene and its RNA transcripts along with evidence equating SRY with the mammalian testisdetermining factor its evolution and biochemical aspects of the SRY protein
Sry the master switch in mammalian sex determination ~ SRY the mammalian Ychromosomal testisdetermining gene induces male sex determination Recent studies in mice reveal that the major role of SRY is to achieve sufficient expression of the related gene Sox9 in order to induce Sertoli cell differentiation which in turn drives testis formation Here we discuss the cascade of events triggered
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